Liposomal Glutathione Benefits

LIPOSOMAL GLUTATHIONE BENEFITS

Glutathione (GSH) is a key intra- and extracellular protective antioxidant with many benefits. It not only recycles other antioxidants such as Vitamin C and E but also sacrifices itself during the process. Free radicals move down the antioxidant chain starting with Vitamin C, E, alpha lipoic acid, and finally glutathione.

Liposomal glutathione and liposomal R-Alpha-Lipoic-Acid are highly
effective thanks to the improved absorption and bioavailability.

Most of us know that inflammation and oxidative stress are the leading cause of chronic diseases today. So, understanding and appreciating why glutathione is critical to every aspect of our health helps us to reduce inflammation and oxidative stress.

Inflammation

Inflammation is an essential and protective response to tissue injury. Acute inflammation is needed to remove the damaging agents and the injured tissues, thereby promoting tissue repair. When this occurs in an uncontrolled manner, and continuously, acute inflammation develops into chronic inflammation.

Oxidative stress

During the acute inflammatory phase, the cells recruit reactive oxygen species (ROS) to the injured site. ROS are metabolic by-products acting as signalling molecules (regulate cell growth and death) and mediators of inflammation. Why are they harmful? Because they oxidize protein and lipid molecules as well as damage DNA. ROS is an essential part of biological processes; however, as with everything else in life, too much of a good thing can be taxing! Oxidative stress means that there are insufficient antioxidant levels in comparison to reactive oxygen and nitrogen species.

Chronic inflammation leads to oxidative stress and vice versa!

Glutathione is the mother of all antioxidants! It has a self-regeneration capacity and is present in every single cell.

Several factors deplete glutathione levels. We invite you to watch the recordings of our webinar to learn more on this by clicking here.

Depleted Glutathione levels are contributing to:

• Neurodegenerative conditions such as Alzheimer’s, Parkinson’s, and Huntington’s
• Pulmonary complications: chronic obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome
• Autoimmunity
• Cholesterol oxidation
• Chronic age-related diseases (cataracts, macular degeneration, hearing impairment and glaucoma)
• Impaired detoxification

Let’s look at the importance of glutathione in detoxification, brain and lung health:

Detoxification

Glutathione is involved in detoxifying xenobiotics (toxins) and other internal compounds
produced by the body. While it exists in every single cell in the body, the concentration is ten times higher in the liver cells. During Phase II liver detoxification, glutathione joins forces with an enzyme called glutathione -s transferase and attaches itself to the toxins. It neutralizes them so they can be expelled from the body without causing damage.

Brain Health

In Alzheimer’s disease, protein deposits, plague forms, and synaptic connection loss occur, leading to cognitive impairment. In addition, the brain is more vulnerable to oxidative damage than other body parts due to the high levels of unsaturated lipids, oxygen, redox metal ions, and poor antioxidant systems.

Lung inflammation

A central feature of lung inflammation – such as idiopathic pulmonary fibrosis, acute
respiratory distress syndrome, cystic fibrosis and asthma – is compromised alveolar and
bronchial function. GSH is important in mitochondrial respiration, immune modulation,
remodelling of the extracellular matrix, and apoptosis (cell death). ROS and reactive nitrogen species (RNS) also act on certain amino acids in proteins (e.g. enzymes, kinases) such as methionine, tyrosine and cysteine, profoundly altering the function of these proteins in inflammatory lung diseases. Some people are more susceptible to lung inflammation due to genetic reasons.

Oxidants are not only produced by metabolic processes; we inhale them. Ozone, cigarette smoking, nitrogen dioxide and sulphur dioxide are exceptionally dangerous and exacerbate the inflammatory process. Tumor Necrosis Factor (TNF-a ) is a pro-inflammatory cytokine recognized as a prime mediator of lung inflammation. If you are genetically prone to have a higher TNF activity – like me – you are more likely to suffer from lung complications. Therefore, liposomal glutathione was an absolute life-saver for me during covid and it had really many benefits.

How can you increase your levels?

Increasing cruciferous vegetables and protein-rich (considering glutathione is a tri-peptide) foods help the production of glutathione. However, I believe this is insufficient – considering the toxic load of today’s pollution and diet – so I recommend supplementing with liposomal glutathione, which really has many benefits. Research confirms that liposomal formulations offer the highest absorption. In addition, alpha-lipoic acid is a great way to stimulate glutathione production.

Sadly, ageing significantly contributes to depleting levels, so I recommend supplementing if you are over thirty. Glutathione levels are lowest in the morning. Therefore, supplementing in the morning on an empty stomach and before bedtime is the most effective way to replenish and ensure better absorption.

How long should glutathione be taken?

At least for one month if you are in good health and looking for maintenance only. I have
seen notable results after two months of consumption, and I believe it is safe for up to three months. However, most research is conducted on six months trials which suggests that it can be taken for up to six months. The typical dosage is between 250 and 1,000mg daily, depending on the person and on the formulation. This is based on my clinical experience.

Liposomal supplements

Powder liposomal supplements are absorbed 20 times better by the body in comparison to regular supplements. You can get maximum effects by consuming lower doses. They are pure, natural, and biocompatible. A game-changing innovative new way to get supplements, preventing stomach acids prematurely breaking down the active ingredients.

If you want to know more about inflammation and how to reduce it, click here to read Anita’s article.

Author: Anita Andor, Women’s Health Specialist – mBANT Nutritional Therapist

References
https://www.sciencedirect.com/science/article/pii/S0925443911002262
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929010/#B285
https://erj.ersjournals.com/content/erj/16/3/534.full.pdf
https://content.iospress.com/articles/journal-of-alzheimers-disease/jad181054
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310837/